All programs work; they only work for so long. Nothing works forever! Louie Simmons said it best “to adapt is not to adapt”. Hans Selye an endocrinologist stated that there are 3 stages of adaptation (Alarm, Resistance, and Exhaustion). One thing to keep in mind is that the body does not differentiate stressors. All stress is stress and is accumulative over time. Training affects 7 different biological systems.